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n-Alcohols Inhibit Voltage-Gated Na(+) Channels Expressed in Xenopus Oocytes
Voltage-gated sodium channels are essential for the initiation and propagation of action potentials in excitable cells and are known as a target of local anesthetics. In addition, inhibition of sodium channels by volatile anesthetics has been proposed as a mechanism of general anesthesia. The n-alco...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575017/ https://ncbi.nlm.nih.gov/pubmed/18434586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.138370 |
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