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Impaired differentiation and apoptosis of hematopoietic precursors in a mouse model of myelodysplastic syndrome
Expression of a NUP98-HOXD13 (NHD13) fusion gene, initially identified in a patient with myelodysplastic syndrome (MDS), leads to a highly penetrant MDS in mice that recapitulates all of the key features of the human disease. Expansion of undifferentiated lineage negative (lin(neg)) hematopoietic pr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575012/ https://ncbi.nlm.nih.gov/pubmed/18603548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.13042 |
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