Coassembly of Different Sulfonylurea Receptor Subtypes Extends the Phenotypic Diversity of ATP-sensitive Potassium (K(ATP)) Channels

K(ATP) channels are metabolic sensors and targets of potassium channel openers (KCO; e.g. diazoxide and pinacidil). They comprise four sulfonylurea receptors (SUR) and four potassium channel subunits (Kir6) and are critical in regulating insulin secretion. Different SUR subtypes (SUR1, SUR2A, SUR2B)...

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Autori principali: Wheeler, Adam, Wang, Chuan, Yang, Ke, Fang, Kun, Davis, Kevin, Styer, Amanda M., Mirshahi, Uyenlinh, Moreau, Christophe, Revilloud, Jean, Vivaudou, Michel, Liu, Shunhe, Mirshahi, Tooraj, Chan, Kim W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574914/
https://ncbi.nlm.nih.gov/pubmed/18723823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.048355
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