Virus-specific intestinal IFN-γ producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs

We examined rotavirus-specific IFN-γ producing CD4+, CD8+ and CD4+CD8+ T cell responses in gnotobiotic pigs infected with a virulent human rotavirus (VirHRV) or vaccinated with an attenuated (Att) HRV vaccine (AttHRV3x or AttHRV2x) or an AttHRV oral priming and 2/6-virus-like particle (VLP) intranas...

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Detalhes bibliográficos
Main Authors: Yuan, Lijuan, Wen, Ke, Azevedo, Marli S.P., Gonzalez, Ana M., Zhang, Wei, Saif, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574896/
https://ncbi.nlm.nih.gov/pubmed/18456375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.03.085
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