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Probiotic Lactobacillus acidophilus enhances the immunogenicity of an oral rotavirus vaccine in gnotobiotic pigs

We evaluated virus-specific B and T cell responses induced by the attenuated Wa (P1A[8]G1) human rotavirus (AttHRV) oral 2-dose vaccine with or without Lactobacillus acidophilus (LA) colonization in neonatal gnotobiotic (Gn) pigs. The AttHRV vaccinated and LA-fed pigs had a significantly higher magn...

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Detalhes bibliográficos
Main Authors: Zhang, Wei, Azevedo, Marli S.P., Wen, Ke, Gonzalez, Ana, Saif, Linda J., Li, Guohua, Yousef, Ahmed E., Yuan, Lijuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491559/
https://ncbi.nlm.nih.gov/pubmed/18524434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.04.070
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