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Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza
The mechanism by which locally delivered sphingosine analogs regulate host response to localized viral infection has never been addressed. In this report, we show that intra-tracheal (i.t.) delivery of chiral sphingosine analog AAL-R or its phosphate ester inhibits the T cell response to influenza-v...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574812/ https://ncbi.nlm.nih.gov/pubmed/18577684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.048769 |
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