Innate immunity and intestinal microbiota in the development of Type 1 diabetes

Type 1 diabetes (T1D) is a debilitating autoimmune disease that results from T cell-mediated destruction of insulin-producing β cells. Its incidence has increased during the past several decades in developed countries 1, 2, suggesting that changes in the environment (including human microbial enviro...

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Hauptverfasser: Wen, Li, Ley, Ruth E., Volchkov, Pavel V., Stranges, Peter B., Avanesyan, Lia, Stonebraker, Austin C., Hu, Changyun, Wong, F. Susan, Szot, Gregory L., Bluestone, Jeffrey A., Gordon, Jeffrey I., Chervonsky, Alexander V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574766/
https://ncbi.nlm.nih.gov/pubmed/18806780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07336
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