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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

Type 1 diabetes (T1D) is a debilitating autoimmune disease that results from T cell-mediated destruction of insulin-producing β cells. Its incidence has increased during the past several decades in developed countries 1, 2, suggesting that changes in the environment (including human microbial enviro...

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Autors principals: Wen, Li, Ley, Ruth E., Volchkov, Pavel V., Stranges, Peter B., Avanesyan, Lia, Stonebraker, Austin C., Hu, Changyun, Wong, F. Susan, Szot, Gregory L., Bluestone, Jeffrey A., Gordon, Jeffrey I., Chervonsky, Alexander V.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574766/
https://ncbi.nlm.nih.gov/pubmed/18806780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07336
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