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Local RNA Conformational Dynamics Revealed by 2-Aminopurine Solvent Accessibility
Acrylamide quenching is widely used to monitor the solvent exposure of fluorescent probes in vitro. Here, we tested the utility of this technique to discriminate local RNA secondary structures using the fluorescent adenine analogue 2-aminopurine (2-AP). Under native conditions, the solvent accessibi...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574756/ https://ncbi.nlm.nih.gov/pubmed/18543944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800487c |
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