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Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol

PURPOSE: Radiation-induced heart disease (RIHD) is a severe side effect of thoracic radiotherapy. This study examined the effects of PTX and α-tocopherol on cardiac injury in a rat model of RIHD. METHODS AND MATERIALS: Male Sprague-Dawley rats received fractionated local heart irradiation with a dai...

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Detalhes bibliográficos
Main Authors: Boerma, Marjan, Roberto, Kerrey A., Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574608/
https://ncbi.nlm.nih.gov/pubmed/18632215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2008.04.042
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