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An Inner-Sphere Mechanism for Molecular Oxygen Reduction Catalyzed by Copper Amine Oxidases

Copper and topaquinone (TPQ) containing amine oxidases utilize O(2) for the metabolism of biogenic amines while concomitantly generating H(2)O(2) for use by the cell. The mechanism of O(2) reduction has been the subject of long-standing debate due to the obscuring influence of a proton-coupled elect...

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Detalhes bibliográficos
Main Authors: Mukherjee, Arnab, Smirnov, Valeriy V., Lanci, Michael P., Brown, Doreen E., Shepard, Eric M., Dooley, David M., Roth, Justine P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574554/
https://ncbi.nlm.nih.gov/pubmed/18582059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja801378f
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