Catalytic Characterization and Cytokine Mediated Regulation of Cytochrome P450 4Fs in Rat Hepatocytes

Cytochrome P450 (CYP) 4F mediated leukotriene B(4) (LTB(4)) metabolism modulates inflammation during injury and infection. Here we show that in addition to LTB(4), the recombinant rat CYP4Fs catalyze omega-hydroxylations of lipoxin A(4), and hydroxyeicosatetraeonic acids. CYP4F gene regulation studi...

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Bibliografiske detaljer
Main Authors: Kalsotra, Auinash, Anakk, Sayeepriyadarshini, Brommer, Chad L, Kikuta, Yasushi, Morgan, Edward T, Strobel, Henry W
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574503/
https://ncbi.nlm.nih.gov/pubmed/17418803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.02.027
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