Catalytic Characterization and Cytokine Mediated Regulation of Cytochrome P450 4Fs in Rat Hepatocytes

Cytochrome P450 (CYP) 4F mediated leukotriene B(4) (LTB(4)) metabolism modulates inflammation during injury and infection. Here we show that in addition to LTB(4), the recombinant rat CYP4Fs catalyze omega-hydroxylations of lipoxin A(4), and hydroxyeicosatetraeonic acids. CYP4F gene regulation studi...

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Autori principali: Kalsotra, Auinash, Anakk, Sayeepriyadarshini, Brommer, Chad L, Kikuta, Yasushi, Morgan, Edward T, Strobel, Henry W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574503/
https://ncbi.nlm.nih.gov/pubmed/17418803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.02.027
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