Modification in penicillin-binding proteins during in vivo development of genetic competence of Haemophilus influenzae is associated with a rapid change in the physiological state of cells.

By using whole-cell labeling assay with 125I-penicillin V, we observed a reduction in the binding of the radiolabeled beta-lactam to four or five penicillin-binding proteins (PBPs) in Haemophilus influenzae cells cultivated under specific conditions. PBPs 3A, 3B, 4, and 6 were altered after the grow...

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Détails bibliographiques

Publié dans:	Infect Immun
Auteurs principaux:	Dargis, M, Gourde, P, Beauchamp, D, Foiry, B, Jacques, M, Malouin, F
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.10.4024-4031.1992
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