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Evidence that autologous idiotypic regulation of anti-arginine-glycine-aspartic acid autoantibodies may influence development and progression of syphilitic lesions in infected rabbits.

The 83-kDa receptor protein of Treponema pallidum (TpN83) recognizes and binds fibronectin (Fn) at the amino acid sequence RGD site. By using experimentally infected animals, we have demonstrated that immunoglobulin G antibodies to this antigen and autoantibodies to the RGD site of Fn are putative c...

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Baughn, R E, Musher, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1500193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3861-3871.1992
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