Arginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding.

Arg-Gly-Asp (RGD)- and fibrinogen gamma-chain carboxyterminal (GQQHHLGGAKQAGDV) peptides inhibit fibrinogen, fibronectin (Fn), vitronectin, and von Willebrand factor (vWF) binding to the platelet glycoprotein IIb-IIIa complex (GP IIb-IIIa). GP IIb-IIIa, vWF, and Fn are essential for normal platelet...

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Bibliografski detalji

Izdano u:	J Clin Invest
Glavni autori:	Lawrence, J B, Kramer, W S, McKeown, L P, Williams, S B, Gralnick, H R
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1990
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2243140/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114896
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