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Synthesis of a conjugate vaccine composed of pneumococcus type 14 capsular polysaccharide bound to pertussis toxin.

Type 14 is one of the common types isolated from patients of all ages with infections caused by Streptococcus pneumoniae. Its capsular polysaccharide (Pn14) is composed of a neutrally charged tetrasaccharide repeat unit. Pn14 does not elicit protective levels of antibodies in infants and children an...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Schneerson, R, Levi, L, Robbins, J B, Bryla, D M, Schiffman, G, Lagergard, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1992
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1500160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3528-3532.1992
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