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Synthesis of a conjugate vaccine composed of pneumococcus type 14 capsular polysaccharide bound to pertussis toxin.

Type 14 is one of the common types isolated from patients of all ages with infections caused by Streptococcus pneumoniae. Its capsular polysaccharide (Pn14) is composed of a neutrally charged tetrasaccharide repeat unit. Pn14 does not elicit protective levels of antibodies in infants and children an...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Schneerson, R, Levi, L, Robbins, J B, Bryla, D M, Schiffman, G, Lagergard, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257356/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1500160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3528-3532.1992
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