Defining Extracellular Integrin α-Chain Sites That Affect Cell Adhesion and Adhesion Strengthening without Altering Soluble Ligand Binding

It was previously shown that mutations of integrin α4 chain sites, within putative EF-hand-type divalent cation-binding domains, each caused a marked reduction in α4β1-dependent cell adhesion. Some reports have suggested that α-chain “EF-hand” sites may interact directly with ligands. However, we sh...

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Publicado en:	Mol Biol Cell
Autores principales:	Pujades, Cristina, Alon, Ronen, Yauch, Robert L., Masumoto, Akihide, Burkly, Linda C., Chen, Chun, Springer, Timothy A., Lobb, Roy R., Hemler, Martin E.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Cell Biology 1997
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9398682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.8.12.2647
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