A Replication-Limited Recombinant Mycobacterium bovis BCG Vaccine against Tuberculosis Designed for Human Immunodeficiency Virus-Positive Persons Is Safer and More Efficacious than BCG

Tuberculosis is the leading cause of death in AIDS patients, yet the current tuberculosis vaccine, Mycobacterium bovis bacillus Calmette-Guérin (BCG), is contraindicated for immunocompromised individuals, including human immunodeficiency virus-positive persons, because it can cause disseminated dise...

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Detalhes bibliográficos
Main Authors: Tullius, Michael V., Harth, Günter, Masleša-Galić, Saša, Dillon, Barbara J., Horwitz, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573348/
https://ncbi.nlm.nih.gov/pubmed/18725418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00434-08
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