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Anaplasma phagocytophilum Increases Cathepsin L Activity, Thereby Globally Influencing Neutrophil Function

Anaplasma phagocytophilum, the agent of human granulocytic anaplasmosis, is an unusual obligate intracellular pathogen that persists in neutrophils. A. phagocytophilum increases the binding of a repressor, CCAAT displacement protein (CDP), to the gp91(phox) promoter, thereby diminishing the host oxi...

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Détails bibliographiques
Auteurs principaux: Thomas, Venetta, Samanta, Swapna, Fikrig, Erol
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573316/
https://ncbi.nlm.nih.gov/pubmed/18765732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00851-08
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