Anaplasma phagocytophilum Utilizes Multiple Host Evasion Mechanisms To Thwart NADPH Oxidase-Mediated Killing during Neutrophil Infection

Anaplasma phagocytophilum, the etiologic agent of human anaplasmosis, is a bacterial pathogen that specifically colonizes neutrophils. Neutrophils utilize the NADPH oxidase complex to generate superoxide (O(2)(−)) and initiate oxidative killing of microorganisms. A. phagocytophilum's unique tro...

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Главные авторы: Carlyon, Jason A., Latif, Dalia Abdel, Pypaert, Marc, Lacy, Paige, Fikrig, Erol
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2004
Предметы:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC470610/
https://ncbi.nlm.nih.gov/pubmed/15271939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4772-4783.2004
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