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Translation Initiation Factor 2γ Mutant Alters Start Codon Selection Independent of Met-tRNA Binding
Selection of the AUG start codon for translation in eukaryotes is governed by codon-anticodon interactions between the initiator Met-tRNA(i)(Met) and the mRNA. Translation initiation factor 2 (eIF2) binds Met-tRNA(i)(Met) to the 40S ribosomal subunit, and previous studies identified Sui(−) mutations...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573310/ https://ncbi.nlm.nih.gov/pubmed/18794367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01147-08 |
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