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Autophosphorylation-Induced Degradation of the Pho85 Cyclin Pcl5 Is Essential for Response to Amino Acid Limitation

Pho85 cyclins (Pcls), activators of the yeast cyclin-dependent kinase (CDK) Pho85, belong together with the p35 activator of mammalian CDK5 to a distinct structural cyclin class. Different Pcls target Pho85 to distinct substrates. Pcl5 targets Pho85 specifically to Gcn4, a yeast transcription factor...

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Detalhes bibliográficos
Main Authors: Aviram, Sharon, Simon, Einav, Gildor, Tsvia, Glaser, Fabian, Kornitzer, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573309/
https://ncbi.nlm.nih.gov/pubmed/18794371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00367-08
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