Growth Determinants for H5N1 Influenza Vaccine Seed Viruses in MDCK Cells

H5N1 influenza A viruses are exacting a growing human toll, with more than 240 fatal cases to date. In the event of an influenza pandemic caused by these viruses, embryonated chicken eggs, which are the approved substrate for human inactivated-vaccine production, will likely be in short supply becau...

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Detalhes bibliográficos
Main Authors: Murakami, Shin, Horimoto, Taisuke, Mai, Le Quynh, Nidom, Chairul A., Chen, Hualan, Muramoto, Yukiko, Yamada, Shinya, Iwasa, Ayaka, Iwatsuki-Horimoto, Kiyoko, Shimojima, Masayuki, Iwata, Akira, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573193/
https://ncbi.nlm.nih.gov/pubmed/18768983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00970-08
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