Eastern and Venezuelan Equine Encephalitis Viruses Differ in Their Ability To Infect Dendritic Cells and Macrophages: Impact of Altered Cell Tropism on Pathogenesis

Eastern and Venezuelan equine encephalitis viruses (EEEV and VEEV, respectively) cause severe morbidity and mortality in equines and humans. Like other mosquito-borne viruses, VEEV infects dendritic cells (DCs) and macrophages in lymphoid tissues, fueling a serum viremia and facilitating neuroinvasi...

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Detalhes bibliográficos
Main Authors: Gardner, Christina L., Burke, Crystal W., Tesfay, Mulu Z., Glass, Pamela J., Klimstra, William B., Ryman, Kate D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573165/
https://ncbi.nlm.nih.gov/pubmed/18768986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01323-08
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