Real-Time PCR Detection of gyrA and parC Mutations in Streptococcus pneumoniae

Fluoroquinolone resistance in Streptococcus pneumoniae mainly involves stepwise mutations predominantly in the parC and gyrA genes. We have developed a single-run real-time PCR assay for detection of the four most common mutations in the quinolone resistance-determining regions of these genes. This...

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Autori principali: Page, S., Vernel-Pauillac, F., O'Connor, O., Bremont, S., Charavay, F., Courvalin, P., Goarant, C., Le Hello, S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573127/
https://ncbi.nlm.nih.gov/pubmed/18725440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00082-08
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