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Oseltamivir-Ribavirin Combination Therapy for Highly Pathogenic H5N1 Influenza Virus Infection in Mice

We studied the effects of a neuraminidase inhibitor (oseltamivir) and an inhibitor of influenza virus polymerases (ribavirin) against two highly pathogenic H5N1 influenza viruses. In vitro, A/Vietnam/1203/04 virus (clade 1) was highly susceptible to oseltamivir carboxylate (50% inhibitory concentrat...

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Main Authors: Ilyushina, Natalia A., Hay, Alan, Yilmaz, Neziha, Boon, Adrianus C. M., Webster, Robert G., Govorkova, Elena A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573119/
https://ncbi.nlm.nih.gov/pubmed/18725448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01579-07
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