Pharmacodynamic Modeling of Aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: Identifying Dosing Regimens To Suppress Resistance Development

To facilitate optimal dosing regimen design, we previously developed a mathematical model using time-kill study data to predict the responses of Pseudomonas aeruginosa to various pharmacokinetic profiles of meropenem and levofloxacin. In this study, we extended the model to predict the activities of...

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Dettagli Bibliografici
Autori principali: Tam, Vincent H., Ledesma, Kimberly R., Vo, Giao, Kabbara, Samer, Lim, Tze-Peng, Nikolaou, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573104/
https://ncbi.nlm.nih.gov/pubmed/18725438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01468-07
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