Inhibition of Renal Rho Kinase Attenuates Ischemia/Reperfusion-Induced Injury

The Rho kinase pathway plays an important role in dedifferentiation of epithelial cells and infiltration of inflammatory cells. For testing of the hypothesis that blockade of this cascade within the kidneys might be beneficial in the treatment of renal injury the Rho kinase inhibitor, Y27632 was cou...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prakash, Jai, de Borst, Martin H., Lacombe, Marie, Opdam, Frank, Klok, Pieter A., van Goor, Harry, Meijer, Dirk K.F., Moolenaar, Frits, Poelstra, Klaas, Kok, Robbert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2008
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573003/
https://ncbi.nlm.nih.gov/pubmed/18650485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007070794
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