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How DNA coiling enhances target localization by proteins
Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial nonspecific binding, they are believed to find the target site by 1D diffusion (“sliding”) intersper...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572962/ https://ncbi.nlm.nih.gov/pubmed/18838672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804248105 |
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