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Septic impairment of capillary blood flow requires NADPH oxidase but not NOS and is rapidly reversed by ascorbate through an eNOS-dependent mechanism

OBJECTIVE: To determine the roles of nitric oxide synthase (NOS) and NADPH oxidase in the impairment of capillary blood flow in sepsis and in the reversal of this impairment by ascorbate. DESIGN: Prospective, controlled laboratory study. SETTING: Animal laboratory in research institute. SUBJECTS: Ad...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tyml, Karel, Li, Fuyan, Wilson, John X.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572871/
https://ncbi.nlm.nih.gov/pubmed/18596627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31818024f6
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