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Methods to Evaluate Biliary Excretion of Drugs in Humans: an Updated Review

Determining the biliary clearance of drugs in humans is very challenging because bile in not readily accessible due to the anatomy of the hepatobiliary tract. The collection of bile usually is limited to post-surgical patients with underlying hepatobiliary disease. In healthy subjects, feces typical...

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Detalhes bibliográficos
Main Authors: Ghibellini, Giulia, Leslie, Elaine M., Brouwer, Kim L.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572858/
https://ncbi.nlm.nih.gov/pubmed/16749853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp060011k
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