Prostaglandin E(2) synergistically with interleukin-23 favors human Th17 expansion

Microenvironment molecular cues direct T helper (Th) cell differentiation; however, Th17 fate determination is still imprecisely understood in humans. To assess the role of prostaglandin E(2) (PGE(2)) in Th expansion, we activated peripheral blood mononuclear cells by CD3 cross-linking. In the prese...

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Detalhes bibliográficos
Main Authors: Chizzolini, Carlo, Chicheportiche, Rachel, Alvarez, Montserrat, de Rham, Casimir, Roux-Lombard, Pascale, Ferrari-Lacraz, Sylvie, Dayer, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572797/
https://ncbi.nlm.nih.gov/pubmed/18698005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155408
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