Prostaglandin E(2) synergistically with interleukin-23 favors human Th17 expansion

Microenvironment molecular cues direct T helper (Th) cell differentiation; however, Th17 fate determination is still imprecisely understood in humans. To assess the role of prostaglandin E(2) (PGE(2)) in Th expansion, we activated peripheral blood mononuclear cells by CD3 cross-linking. In the prese...

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Hlavní autoři: Chizzolini, Carlo, Chicheportiche, Rachel, Alvarez, Montserrat, de Rham, Casimir, Roux-Lombard, Pascale, Ferrari-Lacraz, Sylvie, Dayer, Jean-Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572797/
https://ncbi.nlm.nih.gov/pubmed/18698005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-155408
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