A functional EGF polymorphism, EGF serum levels and esophageal adenocarcinoma risk and outcome

PURPOSE: The epidermal growth factor (EGF) pathway is important in esophageal adenocarcinoma (EAC) tumorigenesis. We hypothesized that the EGF A61G homozygous variant genotype (GG) (i) is both a risk and poor prognostic factor for EAC; and (ii) is associated with higher EGF serum levels in individua...

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Detalhes bibliográficos
Main Authors: Lanuti, Michael, Liu, Geoffrey, Goodwin, Jonathan M., Zhai, Rihong, Fuchs, Bryan C., Asomaning, Kofi, Su, Li, Nishioka, Norman S., Tanabe, Kenneth K., Christiani, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572712/
https://ncbi.nlm.nih.gov/pubmed/18483390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4932
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