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CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

BACKGROUND: A subset of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1(SM)) is involved in the cytoadherence of P. falciparum-infected red blood cells (iRBC) contributing to the pathogenesis of severe disease among young children in malaria endemic areas. The PfEMP1(SM )are encoded...

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Detalhes bibliográficos
Main Authors: Magistrado, Pamela A, Staalsoe, Trine, Theander, Thor G, Hviid, Lars, Jensen, Anja TR
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572619/
https://ncbi.nlm.nih.gov/pubmed/18844973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-204
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