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Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation

BACKGROUND: The development of mass spectrometric techniques and fractionation methods now allows the investigation of very complex protein mixtures ranging from subcellular structures to tissues. Nevertheless, this work is particularly difficult due to the wide dynamic range of protein concentratio...

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Autors principals: Ernoult, Emilie, Gamelin, Erick, Guette, Catherine
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572582/
https://ncbi.nlm.nih.gov/pubmed/18851748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-6-27
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