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Rational attenuation of Corynebacterium pseudotuberculosis: potential cheesy gland vaccine and live delivery vehicle.

The phospholipase D (PLD) gene (pld) has been deleted from the Corynebacterium pseudotuberculosis chromosome by using site-specific mutagenesis. Sheep infection trials indicate that the PLD-negative C. pseudotuberculosis strain (Toxminus) is incapable of inducing caseous lymphadentis (cheesy gland)...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Hodgson, A L, Krywult, J, Corner, L A, Rothel, J S, Radford, A J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1992
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257252/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1612756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.7.2900-2905.1992
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