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Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1

The chromatin regulator Aiolos and the transcriptional coactivator OBF-1 have been implicated in regulating aspects of B cell maturation and activation. Mice lacking either of these factors have a largely normal early B cell development. However, when both factors are eliminated simultaneously a blo...

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Detalhes bibliográficos
Main Authors: Karnowski, Alexander, Cao, Chun, Matthias, Gabriele, Carotta, Sebastian, Corcoran, Lynn M., Martensson, Inga-Lill, Skok, Jane A., Matthias, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571989/
https://ncbi.nlm.nih.gov/pubmed/18974788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003568
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