Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

An effective AIDS vaccine will need to protect against globally diverse isolates of HIV. To address this issue in macaques, we administered a live-attenuated simian immunodeficiency virus (SIV) vaccine and challenged with a highly pathogenic heterologous isolate. Vaccinees reduced viral replication...

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Main Authors: Reynolds, Matthew R., Weiler, Andrea M., Weisgrau, Kim L., Piaskowski, Shari M., Furlott, Jessica R., Weinfurter, Jason T., Kaizu, Masahiko, Soma, Taeko, León, Enrique J., MacNair, Caitlin, Leaman, Dan P., Zwick, Michael B., Gostick, Emma, Musani, Solomon K., Price, David A., Friedrich, Thomas C., Rakasz, Eva G., Wilson, Nancy A., McDermott, Adrian B., Boyle, Rosanne, Allison, David B., Burton, Dennis R., Koff, Wayne C., Watkins, David I.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571929/
https://ncbi.nlm.nih.gov/pubmed/18838548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081524
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