Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

An effective AIDS vaccine will need to protect against globally diverse isolates of HIV. To address this issue in macaques, we administered a live-attenuated simian immunodeficiency virus (SIV) vaccine and challenged with a highly pathogenic heterologous isolate. Vaccinees reduced viral replication...

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Autors principals: Reynolds, Matthew R., Weiler, Andrea M., Weisgrau, Kim L., Piaskowski, Shari M., Furlott, Jessica R., Weinfurter, Jason T., Kaizu, Masahiko, Soma, Taeko, León, Enrique J., MacNair, Caitlin, Leaman, Dan P., Zwick, Michael B., Gostick, Emma, Musani, Solomon K., Price, David A., Friedrich, Thomas C., Rakasz, Eva G., Wilson, Nancy A., McDermott, Adrian B., Boyle, Rosanne, Allison, David B., Burton, Dennis R., Koff, Wayne C., Watkins, David I.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571929/
https://ncbi.nlm.nih.gov/pubmed/18838548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081524
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