Inhibition of RhoA Translocation and Calcium Sensitization by In Vivo ADP-Ribosylation with the Chimeric Toxin DC3B

Pretreatment of intact rabbit portal vein smooth muscle with the chimeric toxin DC3B (10(−6) M, 48 h; Aullo et al., 1993; Boquet et al. 1995) ADP-ribosylated endogenous RhoA, including cytosolic RhoA complexed with rhoGDI, and inhibited the tonic phase of phenylephrine-induced contraction and the Ca...

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Huvudupphovsmän: Fujihara, Hideyoshi, Walker, Lori A., Gong, Ming Cui, Lemichez, Emmanuel, Boquet, Patrice, Somlyo, Avril V., Somlyo, Andrew P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 1997
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC25718/
https://ncbi.nlm.nih.gov/pubmed/9398666
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