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Gradual Phenotypic Conversion Associated with Immortalization of Cultured Human Mammary Epithelial Cells

Examination of the process of immortal transformation in early passages of two human mammary epithelial cell (HMEC) lines suggests the involvement of an epigenetic step. These lines, 184A1 and 184B5, arose after in vitro exposure of finite lifespan 184 HMEC to a chemical carcinogen, and both are clo...

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Detalhes bibliográficos
Main Authors: Stampfer, Martha R., Bodnar, Andrea, Garbe, James, Wong, Michelle, Pan, Alison, Villeponteau, Bryant, Yaswen, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25715/
https://ncbi.nlm.nih.gov/pubmed/9398663
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