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Beta Cells within Single Human Islets Originate from Multiple Progenitors

BACKGROUND: In both humans and rodents, glucose homeostasis is controlled by micro-organs called islets of Langerhans composed of beta cells, associated with other endocrine cell types. Most of our understanding of islet cell differentiation and morphogenesis is derived from rodent developmental stu...

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Detalhes bibliográficos
Main Authors: Scharfmann, Raphaël, Xiao, Xiangwei, Heimberg, Harry, Mallet, Jacques, Ravassard, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571119/
https://ncbi.nlm.nih.gov/pubmed/18958289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003559
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