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Beta Cells within Single Human Islets Originate from Multiple Progenitors

BACKGROUND: In both humans and rodents, glucose homeostasis is controlled by micro-organs called islets of Langerhans composed of beta cells, associated with other endocrine cell types. Most of our understanding of islet cell differentiation and morphogenesis is derived from rodent developmental stu...

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Autori principali: Scharfmann, Raphaël, Xiao, Xiangwei, Heimberg, Harry, Mallet, Jacques, Ravassard, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571119/
https://ncbi.nlm.nih.gov/pubmed/18958289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003559
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