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Amplification of HER2 is a marker for global genomic instability
BACKGROUND: Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given similar treatments, suggests that the effects of ampli...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2571108/ https://ncbi.nlm.nih.gov/pubmed/18854030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-297 |
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