A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition

Cysteine proteases of the Clan CA (papain) family are the predominant protease group in primitive invertebrates. Cysteine protease inhibitors arrest infection by the protozoan parasite, Trypanosoma brucei. RNA interference studies implicated a cathepsin B-like protease, tbcatB, as a key inhibitor ta...

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Xehetasun bibliografikoak
Egile Nagusiak: O'Brien, Theresa C., Mackey, Zachary B., Fetter, Richard D., Choe, Youngchool, O'Donoghue, Anthony J., Zhou, Min, Craik, Charles S., Caffrey, Conor R., McKerrow, James H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Enzyme Catalysis and Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570886/
https://ncbi.nlm.nih.gov/pubmed/18701454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805824200
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