Vaccination of mice with a soluble protein fraction of Mycobacterium leprae provides consistent and long-term protection against M. leprae infection.

Groups of BALB/c mice were vaccinated intradermally with either Freund's incomplete adjuvant (FIA) alone, 10(7) heat-killed Mycobacterium leprae organisms in FIA, or a number of fractions of M. leprae containing soluble and/or cell wall components. At 1, 3, 6, 9, and 12 months later, vaccinated mice...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Gelber, R H, Murray, L, Siu, P, Tsang, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1563772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.5.1840-1844.1992
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