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Effect of low-level and intermittent minocycline therapy on the growth of Mycobacterium leprae in mice.

We evaluated the minimal concentrations of minocycline in the diet and in serum required to inhibit the growth of seven Mycobacterium leprae isolates in mice. Minocycline concentrations of 0.01 and 0.04% in the diet, which resulted in levels in serum of less than or equal to 0.17 and 0.51 microgram/...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Gelber, R H, Siu, P, Tsang, M, Alley, P, Murray, L P
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1991
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1854182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.992
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