Overexpression of artemin in the tongue increases expression of TRPV1 and TRPA1 in trigeminal afferents and causes oral sensitivity to capsaicin and mustard oil

Artemin, a member of the glial cell line-derived neurotrophic factor (GDNF) family, supports a subpopulation of trigeminal sensory neurons through activation of the Ret/GFRα3 receptor tyrosine kinase complex. In a previous study we showed that artemin is increased in inflamed skin of wildtype mice a...

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Main Authors: Elitt, Christopher M., Malin, Sacha A., Koerber, H. Richard, Davis, Brian M., Albers, Kathryn M.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570744/
https://ncbi.nlm.nih.gov/pubmed/18652806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.06.119
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